OS9 (gene) について

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OS9 (gene) ：ウィキペディア英語版

OS9 (gene)

Protein OS-9 is a protein that in humans is encoded by the ''OS9'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10956 )〕

==Model organisms==
Model organisms have been used in the study of OS9 function. A conditional knockout mouse line called ''Os9^{tm1a(EUCOMM)Wtsi}'' was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
{| class="wikitable sortable collapsible collapsed" border="1" cellpadding="2" style="float: left;" |
|+ ''Os9'' knockout mouse phenotype
|-
! Characteristic!! Phenotype
|-
| colspan=2; style="text-align: center;" | All data available at.〔{
|-
| Insulin || bgcolor="#488ED3"|Normal
|-
| Homozygous viability at P14 || bgcolor="#488ED3"|Normal
|-
| Homozygous Fertility || bgcolor="#488ED3"|Normal
|-
| General Observations || bgcolor="#C40000"|Abnormal
|-
| Body weight || bgcolor="#488ED3"|Normal
|-
| Neurological assessment || bgcolor="#488ED3"|Normal
|-
| Grip strength || bgcolor="#488ED3"|Normal
|-
| Dysmorphology || bgcolor="#488ED3"|Normal
|-
| Indirect calorimetry || bgcolor="#488ED3"|Normal
|-
| Glucose tolerance test || bgcolor="#488ED3"|Normal
|-
| Auditory brainstem response || bgcolor="#488ED3"|Normal
|-
| DEXA || bgcolor="#488ED3"|Normal
|-
| Radiography || bgcolor="#488ED3"|Normal
|-
| Eye morphology || bgcolor="#488ED3"|Normal
|-
| Clinical chemistry || bgcolor="#488ED3"|Normal
|-
| ''Haematology'' 16 Weeks || bgcolor="#488ED3"|Normal
|-
| Peripheral blood leukocytes 16 Weeks || bgcolor="#488ED3"|Normal
|-
| Heart weight || bgcolor="#488ED3"|Normal
|-
| ''Salmonella'' infection || bgcolor="#488ED3"|Normal
|-
| Spleen Immunophenotyping || bgcolor="#488ED3"|Normal
|-
| Mesenteric Lymph Node Immunophenotyping || bgcolor="#488ED3"|Normal
|-
| Anti-nuclear Antibody Assay || bgcolor="#488ED3"|Normal
|-
| Epidermal Immune Composition || bgcolor="#488ED3"|Normal
|-
| Influenza Challenge || bgcolor="#488ED3"|Normal
|-
|}''

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抄文引用元・出典: フリー百科事典『ウィキペディア（Wikipedia）』
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